Effective long-range attraction between protein molecules in solutions studied by small angle neutron scattering - art. no. 118402

被引：135

作者：

Liu, Y

Fratini, E

Baglioni, P

Chen, WR

Chen, SH ^{[1
]}

机构：

[1] MIT, Dept Nucl Engn, Cambridge, MA 02139 USA

[2] Univ Florence, Dept Chem, I-50019 Florence, Italy

[3] Univ Florence, CSGI, I-50019 Florence, Italy

来源：

PHYSICAL REVIEW LETTERS | 2005年 / 95卷 / 11期

关键词：

D O I：

10.1103/PhysRevLett.95.118102

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Small angle neutron scattering intensity distributions taken from cytochrome C and lysozyme protein solutions show a rising intensity at a very small wave vector Q, which can be interpreted in terms of the presence of a weak long-range attraction between protein molecules. This interaction has a range several times that of the diameter of the protein molecule, much greater than the range of the screened electrostatic repulsion. We show evidence that this long-range attraction is closely related to the type of anion present and ion concentration in the solution.

引用

页数：4

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