The CD95(APO-1/Fas)/CD95L system

被引:37
作者
Krammer, PH [1 ]
机构
[1] German Canc Res Ctr, Tumorimmunol Program, D-69120 Heidelberg, Germany
关键词
CD95(APO-1/Fas); apoptosis; signaling in apoptosis;
D O I
10.1016/S0378-4274(98)00297-5
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
The CD95 system is one of the best studied death systems and plays an essential role in the immune system, particularly in deletion of peripheral T-cells and in homeostasis of the liver. Here genetic defects in the CD95 system are discussed as well as recent findings of the CD95 signalling pathway. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:131 / 137
页数:7
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