Copper Quantum Clusters in Protein Matrix: Potential Sensor of Pb2+ Ion

被引:323
作者
Goswami, Nirmal [2 ]
Giri, Anupam [2 ]
Bootharaju, M. S. [1 ]
Xavier, Paulrajpillai Lourdu [1 ]
Pradeep, Thalappil [1 ]
Pal, Samir Kumar [2 ]
机构
[1] Indian Inst Technol, Dept Chem, Madras 600036, Tamil Nadu, India
[2] SN Bose Natl Ctr Basic Sci, Dept Chem Biol & Macromol Sci, Kolkata 700098, India
关键词
NANOCLUSTERS; GOLD; NANOPARTICLES; AU-25; DOTS;
D O I
10.1021/ac202610e
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A one-pot synthesis of extremely stable, water-soluble Cu quantum clusters (QCs) capped with a model protein, bovine serum albumin (BSA), is reported. From matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry, we assign the clusters to be composed of Cu-5 and Cu-13 cores. The QCs also show luminescence properties having excitation and emission maxima at 325 and 410 nm, respectively, with a quantum yield of 0.15, which are found to be different from that of protein alone in similar experimental conditions. The quenching of luminescence of the protein-capped Cu QCs in the presence of very low hydrogen peroxide concentration (approximately nanomolar, or less than part-per-billion) reflects the efficacy of the QCs as a potential sensing material in biological environments. Moreover, as-prepared Cu QCs can detect highly toxic Pb2+ ions in water, even at the part-per-million level, without suffering any interference from other metal ions.
引用
收藏
页码:9676 / 9680
页数:5
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