Haematopoiesis - Master regulator unmasked

被引：22

作者：

Green, T

机构：

来源：

NATURE | 1996年 / 383卷 / 6601期

关键词：

D O I：

10.1038/383575a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

收藏

页码：575 / &

页数：2

相关论文

共 14 条

[1] THE SCL GENE-PRODUCT - A POSITIVE REGULATOR OF ERYTHROID-DIFFERENTIATION [J].

APLAN, PD ;

NAKAHARA, K ;

ORKIN, SH ;

KIRSCH, IR .

EMBO JOURNAL, 1992, 11 (11) :4073-4081

[2] ANTISENSE SCL SUPPRESSES SELF-RENEWAL AND ENHANCES SPONTANEOUS ERYTHROID-DIFFERENTIATION OF THE HUMAN LEUKEMIC-CELL LINE K562 [J].

GREEN, AR ;

DELUCA, E ;

BEGLEY, CG .

EMBO JOURNAL, 1991, 10 (13) :4153-4158

[3] ENHANCER-BINDING ACTIVITY OF THE TAL-1 ONCOPROTEIN IN ASSOCIATION WITH THE E47/E12 HELIX-LOOP-HELIX PROTEINS [J].

HSU, HL ;

CHENG, JT ;

CHEN, Q ;

BAER, R .

MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (06) :3037-3042

[4] LOSS OF TAL-1 PROTEIN-ACTIVITY INDUCES PREMATURE APOPTOSIS OF JURKAT LEUKEMIC T-CELLS UPON MEDIUM DEPLETION [J].

LEROYVIARD, K ;

VINIT, MA ;

LECOINTE, N ;

JOUAULT, H ;

HIBNER, U ;

ROMEO, PH ;

MATHIEUMAHUL, D .

EMBO JOURNAL, 1995, 14 (10) :2341-2349

[5] ASSOCIATION OF ERYTHROID TRANSCRIPTION FACTORS - COMPLEXES INVOLVING THE LIM PROTEIN RBTN2 AND THE ZINC-FINGER PROTEIN GATA1 [J].

OSADA, H ;

GRUTZ, G ;

AXELSON, H ;

FORSTER, A ;

RABBITTS, TH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (21) :9585-9589

[6] The T cell leukemia oncoprotein SCL/tal-1 is essential for development of all hematopoietic lineages [J].

Porcher, C ;

Swat, W ;

Rockwell, K ;

Fujiwara, Y ;

Alt, FW ;

Orkin, SH .

CELL, 1996, 86 (01) :47-57

[7] ABSENCE OF YOLK-SAC HEMATOPOIESIS FROM MICE WITH A TARGETED DISRUPTION OF THE SCL GENE [J].

ROBB, L ;

LYONS, I ;

LI, RL ;

HARTLEY, L ;

KONTGEN, F ;

HARVEY, RP ;

METCALF, D ;

BEGLEY, CG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (15) :7075-7079

[8] The helix-loop-helix gene SCL: Implicated in T-cell acute lymphoblastic leukaemia and in normal haematopoietic development [J].

Robb, L ;

Begley, CG .

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 1996, 28 (06) :609-618

[9] The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse [J].

Robb, L ;

Elwood, NJ ;

Elefanty, AG ;

Kontgen, F ;

Li, RL ;

Barnett, LD ;

Begley, CG .

EMBO JOURNAL, 1996, 15 (16) :4123-4129

[10] ABSENCE OF BLOOD FORMATION IN MICE LACKING THE T-CELL LEUKEMIA ONCOPROTEIN TAL-1/SCL [J].

SHIVDASANI, RA ;

MAYER, EL ;

ORKIN, SH .

NATURE, 1995, 373 (6513) :432-434