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Powder-based 3D printing for bone tissue engineering

被引：254
作者：
Brunello, G. [1 ]
Sivolella, S. [1 ]
Meneghello, R. [2 ]
Ferroni, L. [3 ]
Gardin, C. [3 ]
Piattelli, A. [4 ]
Zavan, B. [3 ]
Bressan, E. [1 ]
机构：
[1] Univ Padua, Dept Neurosci, Sect Dent, Via Giustiniani 2, I-35129 Padua, Italy
[2] Univ Padua, Dept Management & Engn, Stradella S Nicola 3, I-36100 Vicenza, Italy
[3] Univ Padua, Dept Biomed Sci, Via Ugo Bassi 58-B, I-35131 Padua, Italy
[4] Univ G dAnnunzio, Dept Med Oral & Biotechnol Sci, Via Vestini 31, I-66100 Chieti, Italy
来源：
BIOTECHNOLOGY ADVANCES | 2016年 / 34卷 / 05期
关键词：
3D printing; Bone; Scaffold; Additive manufacturing technologies; Powder; Binder; Depowdering; Sintering; TRICALCIUM PHOSPHATE SCAFFOLDS; IN-VIVO OSTEOGENESIS; CALCIUM-PHOSPHATE; MECHANICAL-PROPERTIES; DENTAL IMPLANTS; HYDROXYAPATITE SCAFFOLDS; MORPHOGENETIC PROTEIN-2; BIOLOGICAL-PROPERTIES; COMPOSITE SCAFFOLDS; RIDGE AUGMENTATION;
D O I：
10.1016/j.biotechadv.2016.03.009
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 [微生物学]; 090105 [作物生产系统与生态工程];
摘要：
Bone tissue engineered 3-D constructs customized to patient-specific needs are emerging as attractive biomimetic scaffolds to enhance bone cell and tissue growth and differentiation. The article outlines the features of the most common additive manufacturing technologies (3D printing, stereolithography, fused deposition modeling, and selective laser sintering) used to fabricate bone tissue engineering scaffolds. It concentrates, in particular, on the current state of knowledge concerning powder-based 3D printing, including a description of the properties of powders and binder solutions, the critical phases of scaffold manufacturing, and its applications in bone tissue engineering. Clinical aspects and future applications are also discussed. (C) 2016 Elsevier Inc. All rights reserved.
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页码：740 / 753
页数：14
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