A convenient synthesis of amino acid methyl esters

被引：153

作者：

Li, Jiabo ^{[1
]}

Sha, Yaowu ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Key Lab Bioorgan Phosphorous Chem & Chem Biol, Beijing 100084, Peoples R China

来源：

MOLECULES | 2008年 / 13卷 / 05期

关键词：

amino acid methyl ester hydrochlorides; amino acids; trimethylchlorosilane; esterification;

D O I：

10.3390/molecules13051111

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A series of amino acid methyl ester hydrochlorides were prepared in good to excellent yields by the room temperature reaction of amino acids with methanol in the presence of trimethylchlorosilane. This method is not only compatible with natural amino acids, but also with other aromatic and aliphatic amino acids.

引用

页码：1111 / 1119

页数：9

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