Distribution and orientation of genes in the genome of Pyrococcus OT3

被引：9

作者：

Koike, H

Amano, N

Tateno, M

Ohfuku, Y

Suckow, JM

Suzuki, M

机构：

[1] Ctr Struct Biol, CREST, AIST, NIBHT, Tsukuba, Ibaraki 3050046, Japan

[2] Univ Tsukuba, Doctral Program Med Sci, Tsukuba, Ibaraki 3050006, Japan

[3] Univ Tsukuba, Doctral Program Agr Sci, Tsukuba, Ibaraki 3050006, Japan

[4] Univ Tokyo, Grad Sch Human & Environm Sci, Meguro Ku, Tokyo 1530041, Japan

来源：

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES | 1999年 / 75卷 / 02期

关键词：

hyper-thermophile; genome analysis; bacterial evolution; replication; symbiogenesis hypothesis;

D O I：

10.2183/pjab.75.37

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Novel characteristics of genes identified in the genome of a hyper-thermophilic archaebacterium, Pyrococcus sp. OT3, are described by correlating the 1.74 M bases in the circular genome to the 12 hours in a clock. From 0:00 to 7:00 the bases are used to code more for the genes whose transcription takes place in the clockwise direction, while from 7:00 to 12:00 to code more for the genes whose transcription takes place in the anti-clockwise direction. Genes that are closely related to known eubacterial genes distribute equally through the genome without showing any strong position-preference. In contrast, genes that are closely related to known eukaryotic genes have tendency to cluster from 1:30 to 3:30. On the basis of these findings a possible link between transcription and-replication and the origin of archaebacterial genomes are discussed.

引用

页码：37 / 42

页数：6

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