Identifying inner retinal contributions to the human multifocal ERG

被引：92

作者：

Hood, DC

Greenstein, V

Frishman, L

Holopigian, K

Viswanathan, S

Seiple, W

Ahmed, J

Robson, JG

机构：

[1] Columbia Univ, Dept Psychol, New York, NY 10027 USA

[2] NYU, Dept Ophthalmol, New York, NY 10016 USA

[3] Univ Houston, Coll Optometry, Houston, TX 77204 USA

来源：

VISION RESEARCH | 1999年 / 39卷 / 13期

关键词：

electroretinogram; multifocal ERG; glaucoma; diabetes;

D O I：

10.1016/S0042-6989(98)00296-X

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Contributions to the multifocal electroretinogram (ERG) from the inner retina (i.e. ganglion and amacrine cells) were identified by recording from monkeys before and after intravitreal injections of n-methyl DL aspartate (NMDLA) and/or tetrodotoxin (TTX). Components similar in waveform to those removed by the drugs were identified in the human multifocal ERG if the stimulus contrast was set at 50% rather than the typically employed 100% contrast. These components were found to be missing or diminished in the records from some patients with glaucoma and diabetes, diseases which affect the inner retina. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：2285 / 2291

页数：7