Bacterial cell shape

被引:358
作者
Cabeen, MT [1 ]
Jacobs-Wagner, C [1 ]
机构
[1] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1038/nrmicro1205
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Bacterial species have long been classified on the basis of their characteristic cell shapes. Despite intensive research, the molecular mechanisms underlying the generation and maintenance of bacterial cell shape remain largely unresolved. The field has recently taken an important step forward with the discovery that eukaryotic cytoskeletal proteins have homologues in bacteria that affect cell shape. Here, we discuss how a bacterium gains and maintains its shape, the challenges still confronting us and emerging strategies for answering difficult questions in this rapidly evolving field.
引用
收藏
页码:601 / 610
页数:10
相关论文
共 121 条
[81]   Structure of the αβtubulin dimer by electron crystallography [J].
Nogales, E ;
Wolf, SG ;
Downing, KH .
NATURE, 1998, 391 (6663) :199-203
[82]  
PARK JT, 1985, ANN INST PASTEUR MIC, VA136, P51, DOI 10.1016/S0769-2609(85)80021-1
[83]   Dispersed mode of Staphylococcus aureus cell wall synthesis in the absence of the division machinery [J].
Pinho, MG ;
Errington, J .
MOLECULAR MICROBIOLOGY, 2003, 50 (03) :871-881
[84]   ESCHERICHIA-COLI CELL-DIVISION GENE FTSZ ENCODES A NOVEL GTP-BINDING PROTEIN [J].
RAYCHAUDHURI, D ;
PARK, JT .
NATURE, 1992, 359 (6392) :251-254
[85]   ISOLATION AND CHARACTERIZATION OF MUTANTS OF BACILLUS-SUBTILIS AND BACILLUS-LICHENIFORMIS WITH DISTURBED MORPHOLOGY AND CELL DIVISION [J].
ROGERS, HJ ;
MCCONNEL.M ;
BURDETT, IDJ .
JOURNAL OF GENERAL MICROBIOLOGY, 1970, 61 :155-+
[86]  
ROMEIS T, 1994, J BIOL CHEM, V269, P21603
[87]   PENICILLIN-BINDING PROTEIN-7/8 OF ESCHERICHIA-COLI IS A DD-ENDOPEPTIDASE [J].
ROMEIS, T ;
HOLTJE, JV .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1994, 224 (02) :597-604
[88]   Several distinct localization patterns for penicillin-binding proteins in Bacillus subtilis [J].
Scheffers, DJ ;
Jones, LJF ;
Errington, J .
MOLECULAR MICROBIOLOGY, 2004, 51 (03) :749-764
[89]   Cloning and characterization of PBP1C, a third member of the multimodular class A penicillin-binding proteins of Escherichia coli [J].
Schiffer, G ;
Höltje, JV .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (45) :32031-32039
[90]   IDENTIFICATION OF CELL-WALL SUBUNITS IN BACILLUS-SUBTILIS AND ANALYSIS OF THEIR SEGREGATION DURING GROWTH [J].
SCHLAEPPI, JM ;
POOLEY, HM ;
KARAMATA, D .
JOURNAL OF BACTERIOLOGY, 1982, 149 (01) :329-337