The small intestine as a xenobiotic-metabolizing organ

被引：180

作者：

Kaminsky, LS

Zhang, QY

机构：

[1] New York State Dept Hlth, Wadsworth Ctr Labs & Res, Albany, NY 12201 USA

[2] SUNY Albany, Sch Publ Hlth, Dept Environm Hlth & Toxicol, Albany, NY USA

来源：

DRUG METABOLISM AND DISPOSITION | 2003年 / 31卷 / 12期

关键词：

D O I：

10.1124/dmd.31.12.1520

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：1520 / 1525

页数：6

共 93 条

[41] UDP-glucuronosyltransferase UGT1A7 induced in rat small intestinal mucosa by oral administration of 2-naphthoflavone [J].

Kobayashi, T ;

Yokota, H ;

Ohgiya, S ;

Iwano, H ;

Yuasa, A .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1998, 258 (03) :948-955

[42] IDENTIFICATION OF RIFAMPIN-INDUCIBLE P450IIIA4 (CYP3A4) IN HUMAN SMALL-BOWEL ENTEROCYTES [J].

KOLARS, JC ;

SCHMIEDLINREN, P ;

SCHUETZ, JD ;

FANG, C ;

WATKINS, PB .

JOURNAL OF CLINICAL INVESTIGATION, 1992, 90 (05) :1871-1878

[43] Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man [J].

Kupferschmidt, HHT ;

Fattinger, KE ;

Ha, HR ;

Follath, F ;

Krähenbühl, S .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1998, 45 (04) :355-359

[44] Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissue [J].

Lee, JK ;

Bhakta, S ;

Rosen, SD ;

Hemmerich, S .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1999, 263 (02) :543-549

[45]

LEHMANN C, 1973, N-S ARCH PHARMACOL, V276, P89

[46]

Lin JH, 1999, PHARMACOL REV, V51, P135

[47] Co-regulation of CYP3A4 and CYP3A5 and contribution to hepatic and intestinal midazolam metabolism [J].

Lin, YS ;

Dowling, ALS ;

Quigley, SD ;

Farin, FM ;

Zhang, J ;

Lamba, J ;

Schuetz, EG ;

Thummel, KE .

MOLECULAR PHARMACOLOGY, 2002, 62 (01) :162-172

[48]

LOWN KS, 1994, DRUG METAB DISPOS, V22, P947

[49] Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression [J].

Lown, KS ;

Bailey, DG ;

Fontana, RJ ;

Janardan, SK ;

Adair, CH ;

Fortlage, LA ;

Brown, MB ;

Guo, WS ;

Watkins, PB .

JOURNAL OF CLINICAL INVESTIGATION, 1997, 99 (10) :2545-2553

[50] Induction of phase II biotransformation reactions in rat jejunum during lactation. Possible involvement of prolactin [J].

Luquita, MG ;

Catania, VA ;

Pozzi, EJS ;

Vore, M ;

Veggi, LM ;

Pellegrino, JM ;

Mottino, AD .

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1999, 1472 (1-2) :82-92

← 1 2 3 4 5 6 7 8 9 10 →