Functional diversity in the dynamin family

被引：228

作者：

van der Bliek, AM ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Sch Med, Dept Biol Chem, Los Angeles, CA 90095 USA

来源：

TRENDS IN CELL BIOLOGY | 1999年 / 9卷 / 03期

关键词：

D O I：

10.1016/S0962-8924(98)01490-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The function of the GTPase dynamin has been discussed for several years. It clearly plays a role in vesicle budding, but despite recent insights, precisely how it functions in this process is still a matter of debate. In addition, it is now clear that dynamin is a member of a large protein family, present in a variety of cellular locations where members apparently perform a range of functions. This article describes current understanding of the structure and function of the various dynamin family members.

引用

页码：96 / 102

页数：7

共 64 条

[1]

Arnheiter H, 1996, CURR TOP MICROBIOL, V206, P119

[2] Specific role for the PH domain of dynamin-1 in the regulation of rapid endocytosis in adrenal chromaffin cells [J].

Artalejo, CR ;

Lemmon, MA ;

Schlessinger, J ;

Palfrey, HC .

EMBO JOURNAL, 1997, 16 (07) :1565-1574

[3] Synergistic activation of dynamin GTPase by Grb2 and phosphoinositides [J].

Barylko, B ;

Binns, D ;

Lin, KM ;

Atkinson, MAL ;

Jameson, DM ;

Yin, HL ;

Albanesi, JP .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (06) :3791-3797

[4] Differential distribution of dynamin isoforms in mammalian cells [J].

Cao, H ;

Garcia, F ;

McNiven, MA .

MOLECULAR BIOLOGY OF THE CELL, 1998, 9 (09) :2595-2609

[5] Dynamin assembles into spirals under physiological salt conditions upon the addition of GDP and gamma-phosphate analogues [J].

Carr, JF ;

Hinshaw, JE .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (44) :28030-28035

[6] MULTIPLE FORMS OF DYNAMIN ARE ENCODED BY SHIBIRE, A DROSOPHILA GENE INVOLVED IN ENDOCYTOSIS [J].

CHEN, MS ;

OBAR, RA ;

SCHROEDER, CC ;

AUSTIN, TW ;

POODRY, CA ;

WADSWORTH, SC ;

VALLEE, RB .

NATURE, 1991, 351 (6327) :583-586

[7] A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C-elegans [J].

Clark, SG ;

Shurland, DL ;

Meyerowitz, EM ;

Bargmann, CI ;

vanderBliek, AM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (19) :10438-10443

[8]

Estes PS, 1996, J NEUROSCI, V16, P5443

[9] A purified Drosophila septin complex forms filaments and exhibits GTPase activity [J].

Field, CM ;

AlAwar, O ;

Rosenblatt, J ;

Wong, ML ;

Alberts, B ;

Mitchison, TJ .

JOURNAL OF CELL BIOLOGY, 1996, 133 (03) :605-616

[10] Endocytosis proteins and cancer: a potential link? [J].

Floyd, S ;

De Camilli, P .

TRENDS IN CELL BIOLOGY, 1998, 8 (08) :299-301

← 1 2 3 4 5 6 7 →