In vivo He-3 MR images of guinea pig lungs

被引：100

作者：

Black, RD

Middleton, HL

Cates, GD

Cofer, GP

Driehuys, B

Happer, W

Hedlund, LW

Johnson, GA

Shattuck, MD

Swartz, JC

机构：

[1] DUKE UNIV,MED CTR,DEPT PHYS,DURHAM,NC 27710

[2] PRINCETON UNIV,DEPT PHYS,PRINCETON,NJ 08544

来源：

RADIOLOGY | 1996年 / 199卷 / 03期

关键词：

lung; MR; 60.12143; magnetic resonance (MR); contrast enhancement; inert gas imaging; 60.12147;

D O I：

10.1148/radiology.199.3.8638019

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The authors imaged the lungs of live guinea pigs with hyperpolarized (HP) helium-3 as a magnetic resonance (MR) signal source. HP He-3 gas produced through spin exchange with rubidium metal vapor was delivered through an MR-compatible, small-animal ventilator. Two- and three-dimensional lung images acquired with ventilation-gated, radial k-space sampling showed complete ventilation of both lungs. All images were of high quality, demonstrating that HP He-3 allows high-signal-intensity MR imaging in living systems.

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收藏

页码：867 / 870

页数：4

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