Surface modification in microchip electrophoresis

被引：189

作者：

Belder, D ^{[1
]}

Ludwig, M ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, Abt Chromatog, D-45470 Mulheim, Germany

来源：

ELECTROPHORESIS | 2003年 / 24卷 / 21期

关键词：

dynamic coating; electroosmosis; microchip; miniaturization; permanent coating; review; surface modification;

D O I：

10.1002/elps.200305648

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Different approaches and techniques for surface modification of microfluidic devices applied for microchip electrophoresis are reviewed. The main focus is on the improved electrophoretic separation by reducing analyte-wall interactions and manipulation of electroosmosis. Approaches and methods for permanent and dynamic surface modification of microfluidic devices, manufactured from glass, quartz and also different polymeric substrates, are described.

引用

页码：3595 / 3606

页数：12

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