Cocaine-paired cues activate aversive representations in accumbens neurons

被引：4

作者：

Calu, Donna J. ^{[3
]}

Schoenbaum, Geoffrey ^{[1
,2
]}

机构：

[1] Univ Maryland, Sch Med, Dept Anat & Neurobiol, Baltimore, MD 21201 USA

[2] Univ Maryland, Sch Med, Dept Psychiat, Baltimore, MD 21201 USA

[3] Univ Maryland, Sch Med, Program Neurosci, Baltimore, MD 21201 USA

来源：

NEURON | 2008年 / 57卷 / 05期

关键词：

D O I：

10.1016/j.neuron.2008.02.025

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Aversive states are proposed to drive addiction. Here, Wheeler and colleagues show that drug-associated cues come to activate neural representations of aversive information in nucleus accumbens and that this activation predicts subsequent drug use. These remarkable data identify a potential neural substrate through which aversive affective representations may motivate drug use.

引用

页码：633 / 633

页数：1

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