Inhibition of chitin synthase II by catechins from stem bark of Taxus cuspidata

被引：9

作者：

Kim, SU

Hwang, EI

Nam, JY

Son, KH

Bok, SH

Kim, HE

Kwon, BM

机构：

[1] Korea Res Inst Biosci & Biotechnol, KIST, Prot Regulator Res Unit, Taejon 305606, South Korea

[2] Korea Res Inst Biosci & Biotechnol, Plant Protectants RU, Taejon 305606, South Korea

[3] Chungbuk Natl Univ, Coll Agr, Dept Forestry, Cheongju, South Korea

来源：

PLANTA MEDICA | 1999年 / 65卷 / 01期

关键词：

D O I：

10.1055/s-2006-960453

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two flavonoids, (+/-)-catechin and (-)-epicatechin, were isolated from the stem bark of Taxus cuspidata by monitoring chitin synthase II inhibitory activity. The compounds inhibit chitin synthase II with an IC(50) of 15 and 29 mu g/ml, respectively and appear to be selective for chitin synthase II. They did not inhibit chitin synthase III.

引用

页码：97 / 98

页数：2

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