Baylis-Hillman reactions in aqueous acidic media

被引：17

作者：

Caumul, P ^{[1
]}

Hailes, HC ^{[1
]}

机构：

[1] UCL, Dept Chem, London WC1H 0AJ, England

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 47期

基金：

英国工程与自然科学研究理事会;

关键词：

Baylis-Hillman; aqueous reaction conditions; acidic pH;

D O I：

10.1016/j.tetlet.2005.09.130

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Baylis-Hillman reaction has been successfully performed under aqueous acidic conditions at pH 1, using a range of substrates and tertiary amines as catalysts. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：8125 / 8127

页数：3

共 23 条

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[2] Correlation between pKa and reactivity of quinuclidine-based catalysts in the Baylis-Hillman reaction:: Discovery of quinuclidine as optimum catalyst leading to substantial enhancement of scope
Aggarwal, VK
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[J]. JOURNAL OF ORGANIC CHEMISTRY, 2002, 67 (02) : 510 - 514
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[6] ACCELERATION IN WATER OF THE BAYLIS-HILLMAN REACTION
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[J]. TETRAHEDRON LETTERS, 1994, 35 (43) : 7947 - 7948
[7] The Baylis-Hillman reaction: A novel carbon-carbon bond forming reaction
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Rao, PD
Hyma, RS
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[8] Recent advances in the Baylis-Hillman reaction and applications
Basavaiah, D
Rao, AJ
Satyanarayana, T
[J]. CHEMICAL REVIEWS, 2003, 103 (03) : 811 - 891
[9] The aqueous trimethylamine mediated Baylis-Hillman reaction
Basavaiah, D
Krishnamacharyulu, M
Rao, AJ
[J]. SYNTHETIC COMMUNICATIONS, 2000, 30 (11) : 2061 - 2069
[10] BAYLIS AB, Patent No. 3743669

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