Selenenylation-acylation of ketones with 2-chloroselenobenzoyl chloride.: A novel route to benzo[b]selenophenes

被引：22

作者：

Kloc, K ^{[1
]}

Mlochowski, J ^{[1
]}

机构：

[1] Wroclaw Univ Technol, Inst Organ Chem Biochem & Biotechnol, PL-50370 Wroclaw, Poland

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 29期

关键词：

ketones; selenenylation; acylation; benzo[b]selenophenes; 2-chloroselenobenzoyl chloride;

D O I：

10.1016/S0040-4039(01)00839-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

It has been found thar enolizable ketones and 1,3-diones react in neutral or basic medium with biselectrophiles such as 2-chloroselenobenzoyl chloride. The reaction takes place on the active alpha -methylene group. Selenenylation and subsequent acylation of the alpha -carbon atom take place and. depending on the ketone used, 3-hydroxybenzo[b]selenophenes or benzo[b]selenophen-3(2H)-ones are produced in moderate to high yields. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：4899 / 4902

页数：4

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