Synthesis of glycopeptides containing carbohydrate and peptide recognition motifs

被引:297
作者
Herzner, H [1 ]
Reipen, T [1 ]
Schultz, M [1 ]
Kunz, H [1 ]
机构
[1] Johannes Gutenberg Univ Mainz, Inst Organ Chem, D-55128 Mainz, Germany
关键词
D O I
10.1021/cr990308c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Recent efforts and achievements are described, demonstrating how organic chemists are able to turn the task of constructing glycopeptides of enormous complexity into a story of success. The major achievement in glycopeptide chemistry reported during the last five years is highlighted.
引用
收藏
页码:4495 / 4537
页数:43
相关论文
共 265 条
[61]  
GENDLER S, 1988, J BIOL CHEM, V263, P12820
[62]  
Gewehr M, 1997, SYNTHESIS-STUTTGART, P1499
[63]   Human mucin glycoproteins: Varied structures predict diverse properties and specific functions [J].
Gum, JR .
BIOCHEMICAL SOCIETY TRANSACTIONS, 1995, 23 (04) :795-799
[64]   SYNTHESIS OF BETA-D-MANNOSIDES FROM BETA-D-GLUCOSIDES VIA AN INTRAMOLECULAR SN2 REACTION AT C-2 [J].
GUNTHER, W ;
KUNZ, H .
CARBOHYDRATE RESEARCH, 1992, 228 (01) :217-241
[65]   Solid-phase synthesis of a glycosylated peptide fragment of the IL-8 receptor containing two vicinal oligosaccharide chains [J].
Guo, ZW ;
Nakahara, Y ;
Nakahara, Y ;
Ogawa, T .
CARBOHYDRATE RESEARCH, 1997, 303 (03) :373-377
[66]   Solid-phase synthesis of the CD52 glycopeptide carrying an N-linked core pentasaccharide structure [J].
Guo, ZW ;
Nakahara, Y ;
Nakahara, Y ;
Ogawa, T .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1997, 36 (13-14) :1464-1466
[67]   Glycopeptide synthesis using O-pentafluorophenyluronium salts as novel condensing reagents [J].
Habermann, J ;
Kunz, H .
JOURNAL FUR PRAKTISCHE CHEMIE-CHEMIKER-ZEITUNG, 1998, 340 (03) :233-239
[68]   Solid-phase synthesis of a glycopeptide from the homophilic recognition domain of epithelial cadherin 1 using a O-pentafluorophenyluronium salt [J].
Habermann, J ;
Kunz, H .
TETRAHEDRON LETTERS, 1998, 39 (3-4) :265-268
[69]   GLYCOSYLATION OF NUCLEAR AND CYTOPLASMIC PROTEINS IS UBIQUITOUS AND DYNAMIC [J].
HALTIWANGER, RS ;
KELLY, WG ;
ROQUEMORE, EP ;
BLOMBERG, MA ;
DONG, LYD ;
KREPPEL, L ;
CHOU, TY ;
HART, GW .
BIOCHEMICAL SOCIETY TRANSACTIONS, 1992, 20 (02) :264-269
[70]  
Haneda K, 1996, CARBOHYD RES, V292, P61