The IL23 axis plays a key role in the pathogenesis of IBD

被引：167

作者：

McGovern, Dermot ^{[1
]}

Powrie, Fiona ^{[1
]}

机构：

[1] Hammersmith Hosp, Imperial Coll, London W12 0HS, England

来源：

GUT | 2007年 / 56卷 / 10期

关键词：

D O I：

10.1136/gut.2006.115402

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Exciting new results from a genetic study in humans and functional studies in mice have pinpointed interleukin 23 (IL23) and its receptor as a key pathway in the pathogenesis of inflammatory bowel disease (IBD). These findings reveal a hitherto unappreciated role for the IL23 axis in intestinal inflammation and may open new avenues for development of therapeutic strategies in IBD.

引用

页码：1333 / 1336

页数：4

共 35 条

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