Surface modification of poly(dimethylsiloxane) microchannels

被引：459

作者：

Makamba, H ^{[1
]}

Kim, JH ^{[1
]}

Lim, K ^{[1
]}

Park, N ^{[1
]}

Hahn, JH ^{[1
]}

机构：

[1] Pohang Univ Sci & Technol, Dept Chem, Div Mol & Life Sci, Natl Res Lab Adv Biotechnol & Biomed Microinstrum, Pohang 790784, South Korea

来源：

ELECTROPHORESIS | 2003年 / 24卷 / 21期

关键词：

microchannels; poly(dimethylsiloxane); review; surface modification;

D O I：

10.1002/elps.200305627

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This review looks at the efforts that are being made to modify the surface of poly(dimethylsiloxane) (PDMS) microchannels, in order to enhance applicability in the field of microfluidics. Many surface modifications of PDMS have been performed for electrophoretic separations, but new modifications are being done for emerging applications such as heterogeneous immunoassays and cell-based bioassays. These new modification techniques are powerful because they impart biospecificity to the microchannel surfaces and reduce protein adsorption. Most of these applications require the use of aqueous or polar solvents, which makes surface modification a very important topic.

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收藏

页码：3607 / 3619

页数：13

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