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Fluorescent dendrimers with a peptide cathepsin B cleavage site for drug delivery applications

被引：42
作者：
Fuchs, S
Otto, H
Jehle, S
Henklein, P
Schlüter, AD
机构：
[1] Free Univ Berlin, Inst Chem Biochem, D-14195 Berlin, Germany
[2] Free Univ Berlin, Inst Chem Organ Chem, D-14195 Berlin, Germany
[3] Humboldt Univ, Fak Med, Univ Klinikum Charite, D-10098 Berlin, Germany
来源：
CHEMICAL COMMUNICATIONS | 2005年 / 14期
关键词：
D O I：
10.1039/b415651j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The synthesis of a multifunctionally equipped first generation (G1) dendrimer carrying a pentapeptide with a cathepsin B cleavage site, chelating ligands for Pt2+-complexation, and a dansyl fluorescence marker is described and an investigation of its cellular uptake as well as intracellular localization by confocal fluorescence microscopy reported.
引用
收藏
页码：1830 / 1832
页数：3
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