Fluorescent dendrimers with a peptide cathepsin B cleavage site for drug delivery applications

被引：42

作者：

Fuchs, S

Otto, H

Jehle, S

Henklein, P

Schlüter, AD

机构：

[1] Free Univ Berlin, Inst Chem Biochem, D-14195 Berlin, Germany

[2] Free Univ Berlin, Inst Chem Organ Chem, D-14195 Berlin, Germany

[3] Humboldt Univ, Fak Med, Univ Klinikum Charite, D-10098 Berlin, Germany

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 14期

关键词：

D O I：

10.1039/b415651j

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis of a multifunctionally equipped first generation (G1) dendrimer carrying a pentapeptide with a cathepsin B cleavage site, chelating ligands for Pt2+-complexation, and a dansyl fluorescence marker is described and an investigation of its cellular uptake as well as intracellular localization by confocal fluorescence microscopy reported.

引用

页码：1830 / 1832

页数：3

共 35 条

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