Breast cancer: The role of hormone therapy

被引：5

作者：

Creasman, WT ^{[1
]}

机构：

[1] Med Univ S Carolina, Univ Midlife Womens Hlth, Dept Obstet & Gynecol, Mt Pleasant, SC 29464 USA

来源：

SEMINARS IN REPRODUCTIVE MEDICINE | 2005年 / 23卷 / 02期

关键词：

breast cancer; estrogen; progestin; exercise; anthropomorphic factors;

D O I：

10.1055/s-2005-869484

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The possible association of estrogen (E) with or without progestin (P) and breast cancer has been addressed in many studies for several decades. The recent reported prospective double-blind Women's Health Initiative (WHI) study suggests that E + P increases the risk of breast cancer if a woman is an average of 63 years old when she begins replacement therapy. One third of the patients in this study were 70 to 79 years of age when E + P was begun-obviously several decades past menopausal. Retrospective and observational studies suggest protection or no increased risk. The WHI-E only study actually notes a 23% reduction in breast cancer compared with the placebo. It would appear from a review of the literature that if there is an increased risk for breast cancer with E or E + P, it is minimal.

引用

页码：167 / 171

页数：5

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