Genetic imprinting: Silencing elements have their say

被引：18

作者：

Ferguson-Smith, AC ^{[1
]}

机构：

[1] Univ Cambridge, Dept Anat, Cambridge CB2 3DY, England

来源：

CURRENT BIOLOGY | 2000年 / 10卷 / 23期

关键词：

D O I：

10.1016/S0960-9822(00)00817-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Tissue-specific silencing elements have been identified that are required for imprinting of the individual genes in the Igf2-H19 domain of the mouse genome. These elements further elaborate the differences between the two parental chromosomes, and add a new feature toparent-of-origin-specific gene regulatory complexes.

引用

页码：R872 / R875

页数：4

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