Control of a double helix DNA assembly by use of cross-linked oligonucleotides

被引:35
作者
Endo, M [1 ]
Majima, T [1 ]
机构
[1] Osaka Univ, Inst Sci & Ind Res, Ibaraki, Osaka 5670047, Japan
关键词
D O I
10.1021/ja036752l
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Disulfide cross-linked oligonucleotides for connecting two DNA double helixes have been designed, synthesized, and characterized. Employing these cross-linked oligonucleotides, two double helixes can be arranged side by side, and the orientations can be controlled both in parallel and antiparallel ways by addition of a specific complementary DNA strand. Copyright © 2003 American Chemical Society.
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收藏
页码:13654 / 13655
页数:2
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