Why is the clinical acceptance of gonadotropin-releasing hormone antagonist cotreatment during ovarian hyperstimulation for in vitro fertilization so slow?

被引：70

作者：

Fauser, BCJM

Devroey, P

机构：

[1] Univ Utrecht, Ctr Med, Dept Reprod Med, NL-3508 GA Utrecht, Netherlands

[2] Dutch Speaking Free Univ Brussels, Ctr Reprod Med, Brussels, Belgium

来源：

FERTILITY AND STERILITY | 2005年 / 83卷 / 06期

关键词：

D O I：

10.1016/j.fertnstert.2005.02.011

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The use of GnRH antagonist rather than agonist cotreatment during ovarian hyperstimulation for IVF is not widely accepted. Possible benefits, current shortcomings, and avenues for future development are discussed. (c) 2005 by American Society for Reproductive Medicine.

引用

收藏

页码：1607 / 1611

页数：5

相关论文

共 29 条

[21] A randomized comparison of two ovarian stimulation protocols with gonadotropin-releasing hormone (GnRH) antagonist cotreatment for in vitro fertilization commencing recombinant follicle-stimulating hormone on cycle day 2 or 5 with the standard long GnRH agonist protocol [J].

Hohmann, FP ;

Macklon, NS ;

Fauser, BCJM .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (01) :166-173

[22] Contemporary pharmacological manipulation in assisted reproduction [J].

Huirne, JAF ;

Lambalk, CB ;

van Loenen, ACD ;

Schats, R ;

Hompes, PGA ;

Fauser, BCJM ;

Macklon, NS .

DRUGS, 2004, 64 (03) :297-322

[23] Dose-finding study of triptorelin acetate for prevention of a premature LH surge in IVF: a prospective, randomized, double-blind, placebo-controlled study [J].

Janssens, RMJ ;

Lambalk, CB ;

Vermeiden, JPW ;

Schats, R ;

Bernards, JM ;

Rekers-Mombarg, LTM ;

Schoemaker, J .

HUMAN REPRODUCTION, 2000, 15 (11) :2333-2340

[24] Initiation of the gonadotropin-releasing hormone antagonist ganirelix for in vitro fertilization cycles in which the lead follicle is >14 mm [J].

Klipstein, S ;

Reindollar, RH ;

Regan, MM ;

Alper, MM .

FERTILITY AND STERILITY, 2004, 81 (03) :714-715

[25] Prolongation of the follicular phase in in vitro fertilization results in a lower ongoing pregnancy rate in cycles stimulated with recombinant follicle-stimulating hormone and gonadotropin-releasing hormone antagonists [J].

Kolibianakis, EM ;

Albano, C ;

Camus, M ;

Tournaye, H ;

Van Steirteghem, AC ;

Devroey, P .

FERTILITY AND STERILITY, 2004, 82 (01) :102-107

[26] Initiation of gonadotropin-releasing hormone antagonist on day 1 as compared to day 6 of stimulation:: Effect on hormonal levels and follicular development in in vitro fertilization cycles [J].

Kolibianakis, EM ;

Albano, C ;

Camus, M ;

Tournaye, H ;

Van Steirteghem, AC ;

Devroey, P .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (12) :5632-5637

[27] Luteinizing hormone concentrations after gonadotropin-releasing hormone antagonist administration do not influence pregnancy rates in in vitro fertilization-embryo transfer [J].

Merviel, P ;

Antoine, JM ;

Mathieu, E ;

Millot, F ;

Mandelbaum, J ;

Uzan, S .

FERTILITY AND STERILITY, 2004, 82 (01) :119-125

[28] INDUCTION OF OVULATION FOR INVITRO FERTILIZATION USING BUSERELIN AND GONADOTROPINS [J].

PORTER, RN ;

SMITH, W ;

CRAFT, IL ;

ABDULWAHID, NA ;

JACOBS, HS .

LANCET, 1984, 2 (8414) :1284-1285

[29] HUMAN RECOMBINANT FOLLICLE-STIMULATING-HORMONE INDUCES GROWTH OF PREOVULATORY FOLLICLES WITHOUT CONCOMITANT INCREASE IN ANDROGEN AND ESTROGEN BIOSYNTHESIS IN A WOMAN WITH ISOLATED GONADOTROPIN-DEFICIENCY [J].

SCHOOT, DC ;

BENNINK, HJTC ;

MANNAERTS, BMJL ;

LAMBERTS, SWJ ;

BOUCHARD, P ;

FAUSER, BCJM .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1992, 74 (06) :1471-1473