Piperonal as electrophile in the Baylis-Hillman reaction.: A synthesis of hydroxy-β-piperonyl-γ-butyrolactone derivative

被引：66

作者：

Almeida, WP

Coelho, F

机构：

[1] UNICAMP, Inst Quim, Dept Quim Organ, BR-13083970 Sao Paulo, Brazil

[2] Univ Paulista Campinas, Inst Ciencias Saude, Sao Paulo, Brazil

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 47期

关键词：

D O I：

10.1016/S0040-4039(98)01927-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Aromatic aldehydes are reluctant to serve as substrates for the Baylis-Hillman reaction at all under the relatively mild conditions. In our research, we have achieved that piperonal could be an useful substrate in this reaction, employing ultrasound technique. The adduct obtained was used in the preparation of key intermediates for the total synthesis of hydroxylated lignans. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8609 / 8612

页数：4