Dengue nonstructural protein 1 antigen in the urine as a rapid and convenient diagnostic test during the febrile stage in patients with dengue infection

被引：27

作者：

Chuansumrit, Ampaiwan ^{[1
]}

Chaiyaratana, Wathanee ^{[2
]}

Tangnararatchakit, Kanchana ^{[1
]}

Yoksan, Sutee ^{[3
]}

Flamand, Marie ^{[4
]}

Sakuntabhai, Anavaj ^{[5
,6
]}

机构：

[1] Mahidol Univ, Ramathibodi Hosp, Fac Med, Dept Pediat, Bangkok 10400, Thailand

[2] Mahidol Univ, Ramathibodi Hosp, Fac Med, Res Ctr, Bangkok 10400, Thailand

[3] Mahidol Univ, Inst Mol Biosci, Ctr Vaccine Dev, Nakhon Pathom 73170, Thailand

[4] Inst Pasteur, Unite Genet Mol Bunyavirus, Paris, France

[5] Mahidol Univ, Fac Sci, Ctr Excellence Vector & Vector Borne Dis, Bangkok 10400, Thailand

[6] Inst Pasteur, Unite Pathogenie Virale, Paris, France

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2011年 / 71卷 / 04期

关键词：

Dengue nonstructural protein 1 antigen; NS1; Urine; Dengue infection; Early dengue diagnosis; VIRUS; SALIVA;

D O I：

10.1016/j.diagmicrobio.2011.08.020

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A total of 136 matched serum and urine samples obtained from 55 patients with dengue infection and 30 other febrile illnesses were assayed for dengue nonstructural protein 1 (NS1) antigen. The urine NS1 ELISA was positive in patients with dengue fever (68.4%) and dengue hemorrhagic fever (63.9%), whereas the strip method showed a lower positive rate. (C) 2011 Elsevier Inc. All rights reserved.

引用

页码：467 / 469

页数：3

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