Synthesis of β-substituted cationic porphyrins and their interactions with DNA

被引：14

作者：

Chen, B

Qin, W

Wang, P

Tian, T

Ma, HJ

Cao, XP

Wu, XJ

Zhou, X ^{[1
]}

Zhang, XL

Liu, F

Zheng, F

Li, X

机构：

[1] Wuhan Univ, Sch Med, Wuhan 430072, Peoples R China

[2] Wuhan Univ, Coll Chem & Mol Sci, Wuhan 430072, Peoples R China

[3] Lanzhou Univ, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2003年 / 13卷 / 21期

关键词：

D O I：

10.1016/j.bmcl.2003.08.016

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The beta-substituted cationic porphyrins (7, 8 and 10) have been synthesized and their interactions with plasmid DNA investigated. We found that substituents at the beta-position of porphyrins (7 and 8) have apparently affected their interactions with DNA compared with non-beta-substituted porphyrins (10). (C) 2003 Elsevier Ltd. All rights reserved.

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页码：3731 / 3733

页数：3

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