α-glucosidase inhibitory activity of triterpenoids from Cichorium intybus

被引：68

作者：

Atta-Ur-Rahman ^{[1
]}

Zareen, Seema ^{[1
]}

Choudhary, M. Iqbal ^{[1
]}

Akhtar, M. Nadeern ^{[1
]}

Khan, Shamsun Nahar ^{[1
]}

机构：

[1] Univ Karachi, HEJ Res Inst Chem, Int Ctr Chem & Biol Sci, Karachi 75270, Pakistan

来源：

JOURNAL OF NATURAL PRODUCTS | 2008年 / 71卷 / 05期

关键词：

D O I：

10.1021/np800001v

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new triterpenoids, 18 alpha, 19 beta-20(30)-taraxasten-3 beta,21 alpha-diol (cichoridiol) (1) and 17-epi-methyl-6-hydroxyangolensate (intybusoloid) (2), were obtained from the methanolic extract of seeds of Cichorium intybus along with 11 known compounds, lupeol (3), friedelin (4), beta-sitosterol (5), stigmasterol (6), betulinic acid (7), betulin (8), betulinaldehyde (9), syringic acid (10), vanillic acid (11) 6,7-dihydroxycoumarin (12), and methyl-alpha-D-galactopyranoside (13). Compounds 1, 1a, and 11 showed a good alpha-glucosidase inhibitory activity.

引用

页码：910 / 913

页数：4

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