An inventory of the P-type ATPases in the fission yeast Schizosaccharomyces pombe

被引：11

作者：

Okorokova-Façanha, AL

Okorokov, LA

Ekwall, K

机构：

[1] Univ Estadual Norte Fluminense, Lab Fisiol & Bioquim Microorganismos, Ctr Biociencias & Biotecnol, BR-28013600 Campos Dos Goytacazes, Brazil

[2] Univ Coll Sodertorn, Dept Biosci, Novum, Dept Nat Sci,Karolinska Inst, S-14189 Huddinge, Sweden

来源：

CURRENT GENETICS | 2003年 / 43卷 / 04期

关键词：

fission yeast; membrane transport P-type ATPase; phylogenetic relationship;

D O I：

10.1007/s00294-003-0395-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The analysis of the Schizosaccharomyces pombe genome revealed the presence of 14 putative P-type ATPases. The clustering of ATPases resembles that of Saccharomyces cerevisiae, indicating that the main classes of pumps were already present before the split of the Archiascomycetes from the other Ascomycota. The overall amino acid identity between fission and budding yeast P-type ATPases is generally low (30-50%). This is similar to the fungus-plant and fungus-animal comparisons.. suggesting that fungal ATPases underwent an extensive process of diversification. Unlike Sac. cerevisiae. fission yeast lacks Na+-ATPases, has a single heavy-metal ATPase and three ATPases of unknown specificity. The observed divergence within these fungi might reflect physiological differences, including adaptation to environmental stresses.

引用

页码：273 / 280

页数：8