A feasibility study of image-guided hypofractionated conformal arc therapy for inoperable patients with localized non-smatt cell lung cancer

被引：13

作者：

Bral, Samuel ^{[1
]}

Van Parijs, Hitde

Soete, Guy

Linthout, Nadine

Van Moorter, Lutgard

Verellen, Dirk

Storme, Guy

机构：

[1] Univ Hosp Brussels, Dept Radiotherapy, Brussels, Belgium

[2] Algemeen Stedelijk Ziekenhuis, Dept Pneumol, Aalst, Belgium

来源：

RADIOTHERAPY AND ONCOLOGY | 2007年 / 84卷 / 03期

关键词：

lung cancer; hypofractionation; conformal radiotherapy; image-guided radiotherapy;

D O I：

10.1016/j.radonc.2007.07.010

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We treated 36 cases of stage I/II non-small cell lung cancer in inoperable patients. Treatments were planned to a total isocenter dose of 60 Gy (8 x 7.5 Gy) based on a dynamic field shaping arc, employing one arc to span as much area as possible and if needed additional weighted segments. The 2 year infield progression free probability is 65%. Disease-specific survival is 75% at 2 years. No patients experienced grade 3-4 toxicity. (C) 2007 Elsevier Ireland Ltd. All rights reserved.

引用

页码：252 / 256

页数：5

共 23 条

[1] Can pet provide the 3D extent of tumor motion for individualized internal target volumes? A phantom study of the limitations of CY and the promise of PET [J].

Caldwell, CB ;

Mah, K ;

Skinner, M ;

Danjoux, CE .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2003, 55 (05) :1381-1393

[2] Percutaneous placement of marking coils before stereotactic radiation therapy of malignant lung lesions [J].

de Mey, J ;

Van de Steene, J ;

Vandenbroucke, F ;

Verellen, D ;

Trappeniers, L ;

Meysman, M ;

Everaert, H ;

Noppen, M ;

Storme, G ;

Bossuyt, A .

JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY, 2005, 16 (01) :51-56

[3] Small-volume image-guided radiotherapy using hypofractionated, coplanar, and noncoplanar multiple fields for patients with inoperable stage I nonsmall cell lung carcinomas [J].

Fukumoto, S ;

Shirato, H ;

Shimzu, S ;

Ogura, S ;

Onimaru, R ;

Kitamura, K ;

Yamazaki, K ;

Miyasaka, K ;

Nishimura, M ;

Dosaka-Akita, H .

CANCER, 2002, 95 (07) :1546-1553

[4] Stereotactic single-dose radiotherapy of Stage I non-small-cell lung cancer (NSCLC) [J].

Hof, H ;

Herfarth, KK ;

Münter, M ;

Hoess, A ;

Motsch, J ;

Wannenmacher, M ;

Debus, J .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2003, 56 (02) :335-341

[5] Prospective study on stereotactic radiotherapy of limited-stage non-small-cell lung cancer [J].

Hoyer, Morten ;

Roed, Henrik ;

Hansen, Anders Traberg ;

Ohlhuis, Lars ;

Petersen, Jorgen ;

Nellemann, Hanne ;

Berthelsen, Anne Kiil ;

Grau, Cai ;

Engelholm, Svend Aage ;

Von Der Maase, Hans .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 66 (04) :S128-S135

[6] DYNAMIC FIELD SHAPING TO OPTIMIZE STEREOTAXIC RADIOSURGERY [J].

LEAVITT, DD ;

GIBBS, FA ;

HEILBRUN, MP ;

MOELLER, JH ;

TAKACH, GA .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1991, 21 (05) :1247-1255

[7] Evaluation of dose calculation algorithms for dynamic arc treatments of head and neck tumors [J].

Linthout, N ;

Verellen, D ;

Van Acker, S ;

Voordeckers, M ;

Bretz, A ;

Storme, G .

RADIOTHERAPY AND ONCOLOGY, 2002, 64 (01) :85-95

[8] Stereotactic body radiation therapy of early-stage non-small-cell lung carcinoma: Phase I study [J].

McGarry, RC ;

Papiez, L ;

Williams, M ;

Whitford, T ;

Timmerman, RD .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2005, 63 (04) :1010-1015

[9]

MORRISON R, 1963, LANCET, V1, P683

[10] Clinical outcomes of a phase I/II study of 48 Gy of stereotactic body radiotherapy in 4 fractions for primary lung cancer using a stereotactic body frame [J].

Nagata, Y ;

Takayama, K ;

Matsuo, Y ;

Norihisa, Y ;

Mizowaki, T ;

Sakamoto, T ;

Sakamoto, M ;

Mitsumori, M ;

Shibuya, K ;

Araki, N ;

Yano, S ;

Hiraoka, M .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2005, 63 (05) :1427-1431

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