Genetic counselling for schizophrenia in the era of molecular genetics

被引:37
作者
Hodgkinson, KA
Murphy, J
O'Neill, S
Brzustowicz, L
Bassett, AS
机构
[1] Ctr Addict & Mental Hlth, Queen St Div, Schizophrenia Res Program, Genet Sect, Toronto, ON M6J 1H4, Canada
[2] Mem Univ Newfoundland, Dept Genet, St John, NF, Canada
[3] Univ Med & Dent New Jersey, Dept Genet, Piscataway, NJ 08854 USA
[4] Univ Med & Dent New Jersey, Dept Psychiat, Piscataway, NJ 08854 USA
[5] Univ Toronto, Dept Psychiat, Toronto, ON, Canada
来源
CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE | 2001年 / 46卷 / 02期
关键词
genetic counselling; schizophrenia; 22q deletion syndrome; psychiatric genetics;
D O I
10.1177/070674370104600202
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: To review the role of genetic counselling for individuals with psychiatric illnesses. Method: Using schizophrenia as an example and including updated information about a genetic subtype (22q deletion syndrome), we discuss the value of the genetic counselling process in psychiatry, with support from the literature and our clinical experience. Results: Genetic counselling, the process through which knowledge about the genetics of illnesses is shared, provides information on the inheritance of illnesses and their recurrence risks; addresses the concerns of patients, their families, and their health care providers: and supports patients and their families dealing with these illnesses. For comprehensive medical management, this service should be available to all individuals with schizophrenia and their families. Conclusions: New findings in the genetics of psychiatric illness may have important clinical implications for patients and their families.
引用
收藏
页码:123 / 130
页数:8
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