What is the real role of antimicrobial polypeptides that can mediate several other inflammatory responses?

被引:109
作者
Elsbach, P [1 ]
机构
[1] NYU, Sch Med, Dept Med, New York, NY 10016 USA
关键词
D O I
10.1172/JCI200318761
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 [基础医学];
摘要
Antimicrobial peptides are effector molecules of innate immunity with microbicidal and pro- or anti-inflammatory activities. Their role is now widening following evidence that one such multifunctional peptide, LL-37, induces angiogenesis, a process essential for host defense, wound healing, and tissue repair (see related article beginning on page 1665).
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页码:1643 / 1645
页数:3
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