Rapid detection of the pandemic methicillin-resistant Staphylococcus aureus clone ST 239, a dominant strain in Asian hospitals

被引：58

作者：

Feil, Edward J. ^{[1
]}

Nickerson, Emma K. ^{[2
,3
]}

Chantratita, Narisara ^{[2
]}

Wuthiekanun, Vanaporn ^{[2
]}

Srisomang, Pramot ^{[4
]}

Cousins, Richard ^{[1
]}

Pan, WuBin ^{[5
]}

Zhang, Ge ^{[5
]}

Xu, BangLao ^{[5
,6
]}

Day, Nicholas P. J. ^{[2
,3
]}

Peacock, Sharon J. ^{[2
,3
]}

机构：

[1] Univ Bath, Dept Biol & Biochem, Bath BA2 7AY, Avon, England

[2] Mahidol Univ, Fac Trop Med, Mahidol Oxford Trop Med Res Unit, Bangkok 10400, Thailand

[3] Univ Oxford, Churchill Hosp, Nuffield Dept Clin Med, Ctr Clin Vaccinol & Trop Med, Oxford OX3 7LJ, England

[4] Sappasithiprasong Hosp, Ubon Ratchathani 34000, Thailand

[5] Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510080, Peoples R China

[6] Guangzhou First Municipal Peoples Hosp, Clin Microbiol Lab, Guangzhou 510080, Peoples R China

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2008年 / 46卷 / 04期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/JCM.02238-07

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We describe and validate a novel PCR assay to detect the pandemic hospital-acquired metbicillin-resistant Staphylococcus aureus (RA-MRSA) lineage ST 239. Results based on previously uncharacterized isolates from a hospital in northeast Thailand support the view that at least 90% of RA-MRSA isolates in mainland Asia correspond to ST 239 or close relatives.

引用

页码：1520 / 1522

页数：3

共 21 条

[1] The predominant variant of the Brazilian epidemic clonal complex of methicillin-resistant Staphylococcus aureus has an enhanced ability to produce biofilm and to adhere to and invade airway epithelial cells [J].

Amaral, MM ;

Coelho, LR ;

Flores, RP ;

Souza, RR ;

Silva-Carvalho, MC ;

Teixeira, LA ;

Ferrerira-Carvalho, BT ;

Figueiredo, AMS .

JOURNAL OF INFECTIOUS DISEASES, 2005, 192 (05) :801-810

[2] Changes in the clonal nature and antibiotic resistance profiles of methicillin-resistant Staphylococcus aureus isolates associated with spread of the EMRSA-15 clone in a tertiary care Portuguese hospital [J].

Amorim, M. L. ;

Faria, N. A. ;

Oliveira, D. C. ;

Vasconcelos, C. ;

Cabeda, J. C. ;

Mendes, A. C. ;

Calado, E. ;

Castro, A. P. ;

Ramos, M. H. ;

Amorim, J. M. ;

de Lencastre, H. .

JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (09) :2881-2888

[3] Staphylococcal cassette chromosome mec (SCCmec) typing of methicillin-resistant Staphylococcus aureus strains isolated in 11 Asian countries:: a proposal for a new nomenclature for SCCmec elements [J].

Chongtrakool, P ;

Ito, T ;

Ma, XX ;

Kondo, Y ;

Trakulsomboon, S ;

Tiensasitorn, C ;

Chavalit, T ;

Song, JH ;

Hiramatsu, K .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (03) :1001-1012

[4] Replacement of methicillin-resistant Staphylococcus aureus clones in Hungary over time:: a 10-year surveillance study [J].

Conceicao, T. ;

Aires-de-Sousa, M. ;

Fuzi, M. ;

Toth, A. ;

Paszti, J. ;

Ungvari, E. ;

van Leeuwen, W. B. ;

van Belkum, A. ;

Grundmann, H. ;

de Lencastre, H. .

CLINICAL MICROBIOLOGY AND INFECTION, 2007, 13 (10) :971-979

[5] The phylogeny of Staphylococcus aureus -: which genes make the best intra-species markers? [J].

Cooper, Jessica E. ;

Feil, Edward J. .

MICROBIOLOGY-SGM, 2006, 152 :1297-1305

[6] A MAJOR OUTBREAK OF METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS CAUSED BY A NEW PHAGE-TYPE (EMRSA-16) [J].

COX, RA ;

CONQUEST, C ;

MALLAGHAN, C ;

MARPLES, RR .

JOURNAL OF HOSPITAL INFECTION, 1995, 29 (02) :87-106

[7]

de Lencastre Herminia, 1997, Clin Microbiol Infect, V3, P289

[8] Intercontinental spread of a multidrug-resistant methicillin-resistant Staphylococcus aureus clone [J].

de Sousa, MA ;

Sanches, IS ;

Ferro, ML ;

Vaz, MJ ;

Saraiva, Z ;

Tendeiro, T ;

Serra, J ;

de Lencastre, H .

JOURNAL OF CLINICAL MICROBIOLOGY, 1998, 36 (09) :2590-2596

[9] Survey of infections due to Staphylococcus species:: Frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997-1999 [J].

Diekema, DJ ;

Pfaller, MA ;

Schmitz, FJ ;

Smayevsky, J ;

Bell, J ;

Jones, RN ;

Beach, M .

CLINICAL INFECTIOUS DISEASES, 2001, 32 :S114-S132

[10] An outbreak in an intensive care unit of a strain of methicillin-resistant Staphylococcus aureus sequence type 239 associated with an increased rate of vascular access device-related bacteremia [J].

Edgeworth, Jonathan D. ;

Yadegarfar, Ghasem ;

Pathak, Smriti ;

Batra, Rahul ;

Cockfield, Joshua D. ;

Wyncoll, Duncan ;

Beale, Richard ;

Lindsay, Jodi A. .

CLINICAL INFECTIOUS DISEASES, 2007, 44 (04) :493-501

← 1 2 3 →