Asymmetric catalysis with bifunctional cinchona alkaloid-based urea and thiourea organocatalysts

被引:773
作者
Connon, Stephen J. [1 ]
机构
[1] Univ Dublin, Ctr Synth & Chem Biol, Sch Chem, Trinity Coll, Dublin 2, Ireland
关键词
D O I
10.1039/b719249e
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Cinchona alkaloid derivatives modified to include a (thio) urea component have emerged in the last three years as readily accessible, robust and tunable bifunctional organocatalysts for a range of synthetically useful transformations. The origins of these catalysts and the major developments in their application in enantioselective synthesis are reviewed.
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收藏
页码:2499 / 2510
页数:12
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