Identification of a novel subset of T lymphocytes in patients with balkanic nephropathy

被引：5

作者：

Drugarin, D ^{[1
]}

Tatu, C ^{[1
]}

Noveanu, L ^{[1
]}

Paunescu, V ^{[1
]}

机构：

[1] MED UNIV TIMISOARA,DEPT PHYSIOL,TIMISOARA,ROMANIA

来源：

AUTOIMMUNITY | 1996年 / 23卷 / 02期

关键词：

Balkanic Nephropathy; CD3(+)CD16(+)CD56(+) T cells subset; CD3(+) CD16(+)16(+)CD56(+) T cells immunophenotyping; immunopathological mechanisms;

D O I：

10.3109/08916939608995335

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Balkanic Nephropathy (BN) is characterized by: an incidence limited to a geographic area: a familial character and a slow progressive evoluation towards chronic renal failure associated with the symmetrical reduction of the kidney size, The etiology of BN is unknown. The aim of our study was to find out the immune alterations in BN pathology. In the BN patients we identified a novel subset of the CD3(+)CD16(+)CD56(+) T cells expressing the phenotypic characteristics of both T lymphocytes and NK cells, The analysis of various subpopulations of lymphocytes, however, showed no quantitative differences in comparison with healthy subjects and healthy subjects from the endemic area.

引用

页码：119 / 126

页数：8

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