A Low-Concentration Hydrothermal Synthesis of Biocompatible Ordered Mesoporous Carbon Nanospheres with Tunable and Uniform Size

被引:649
作者
Fang, Yin [1 ,2 ]
Gu, Dong [1 ,2 ]
Zou, Ying [1 ,2 ]
Wu, Zhangxiong [1 ,2 ]
Li, Fuyou [1 ,2 ]
Che, Renchao [1 ,2 ]
Deng, Yonghui [1 ,2 ]
Tu, Bo [1 ,2 ]
Zhao, Dongyuan [1 ,2 ]
机构
[1] Fudan Univ, Dept Chem, Adv Mat Lab, Shanghai 200433, Peoples R China
[2] Fudan Univ, Shanghai Key Lab Mol Catalysis & Innovat Mat, Shanghai 200433, Peoples R China
关键词
carbon; drug delivery; hydrothermal synthesis; mesoporous materials; nanoparticles; CONTROLLED-RELEASE; SILICA NANOPARTICLES; ASSISTED SYNTHESIS; DELIVERY-SYSTEM; DRUG-DELIVERY; SPHERES; PARTICLES; POLYMERS; POROSITY; SHELL;
D O I
10.1002/anie.201002849
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Mesoporous carbon nanoparticles with uniform spherical morphology were fabricated through a low-concentration hydrothermal synthesis route. The diameters can be tuned from 20 to 140 nm by varying the reagent concentration. The highly ordered mesoporous carbon nanospheres with high surface area and large pore volume show low cytotoxicity and can easily penetrate into living cells. © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:7987 / 7991
页数:5
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