Characterization of the mouse Cblc/Cbl3 gene

被引：5

作者：

Fiore, F ^{[1
]}

Ollendorff, V ^{[1
]}

Birnbaum, D ^{[1
]}

机构：

[1] INSERM, U119, Oncol Mol Lab, F-13009 Marseille, France

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 2001年 / 280卷 / 01期

关键词：

D O I：

10.1006/bbrc.2000.4116

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mouse Cblc/Cbl3 gene was cloned and characterized. It comprises 12 exons and encodes a putative protein of 496 amino acid residues which shares an overall 67% identity with its human ortholog; it also shares 70% of amino acid identity with mouse CBL over their conserved SH2 and Ring finger domains. Mouse Cblc mRNA is expressed in embryo and adult tissues and has a rather ubiquitous distribution. (C) 2001 Academic Press.

引用

页码：182 / 187

页数：6

共 25 条

[21]

PHILIPPE JM, 1998, IN EQUENTIAL SITU HY

[22] Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7 [J].