Role of the stationary growth phase sigma factor RpoS of Burkholderia pseudomallei in response to physiological stress conditions

被引:36
作者
Subsin, B
Thomas, MS
Katzenmeier, G
Shaw, JG
Tungpradabkul, S
Kunakorn, M
机构
[1] Mahidol Univ, Fac Sci, Ramathibodi Hosp, Dept Pathol, Bangkok 10400, Thailand
[2] Mahidol Univ, Fac Sci, Dept Biochem, Bangkok 10400, Thailand
[3] Univ Sheffield, Sch Med, Div Genom Med, Sheffield, S Yorkshire, England
[4] Mahidol Univ, Inst Mol Biol & Genet, Nakhon Pathom, Thailand
关键词
D O I
10.1128/JB.185.23.7008-7014.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The Burkholderia pseudomallei rpoS gene was identified, and an rpoS null mutant was constructed. The mutant was shown to have an increased sensitivity to carbon starvation and oxidative stress. By using rpoS-lacZ fusions, transcription of rpoS was shown to be growth phase regulated, reaching a peak upon entry into stationary phase.
引用
收藏
页码:7008 / 7014
页数:7
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