Formation of benzo[b]fluorenes and the benzo[a]fluorene core of the fluostatins by cyclization of diaryldiynones

被引：49

作者：

Atienza, C ^{[1
]}

Mateo, C ^{[1
]}

de Frutos, O ^{[1
]}

Echavarren, AM ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Dept Quim Organ, E-28049 Madrid, Spain

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 02期

关键词：

D O I：

10.1021/ol0067336

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Thermal cyclization of 1-[2-(trimethylsiiylethynyl)phenyl]-3-arylpropinones was expected to give benzo[b]fluorenones. However, benzo[a] fluorenones were also formed as a result of a new rearrangement. These tetracycles possess the core structure of the fluostatins and isoprekinamycin.

引用

页码：153 / 155

页数：3

共 42 条

[41] Intramolecular [4+2] cycloaddition reactions of conjugated ynones. Formation of polycyclic furans via the generation and rearrangement of strained heterocyclic allenes
Wills, MSB
Danheiser, RL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (36) : 9378 - 9379
[42] Synthesis of a C44H26 hydrocarbon having a carbon framework represented on the surface of C60 via benzoenyne-allenes
Zhang, HR
Wang, KK
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1999, 64 (21) : 7996 - 7999

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