Formation of benzo[b]fluorenes and the benzo[a]fluorene core of the fluostatins by cyclization of diaryldiynones

被引:49
作者
Atienza, C [1 ]
Mateo, C [1 ]
de Frutos, O [1 ]
Echavarren, AM [1 ]
机构
[1] Univ Autonoma Madrid, Dept Quim Organ, E-28049 Madrid, Spain
关键词
D O I
10.1021/ol0067336
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
[GRAPHICS] Thermal cyclization of 1-[2-(trimethylsiiylethynyl)phenyl]-3-arylpropinones was expected to give benzo[b]fluorenones. However, benzo[a] fluorenones were also formed as a result of a new rearrangement. These tetracycles possess the core structure of the fluostatins and isoprekinamycin.
引用
收藏
页码:153 / 155
页数:3
相关论文
共 42 条