Microbial reduction of methyl-substituted bicyclo[3.2.0]hept-3-en-6-ones: A screening to homochiral endo- and exo-alcohols

被引：11

作者：

Fantin, G

Fogagnolo, M

Medici, A

Pedrini, P

Marotta, E

Monti, M

Righi, P

机构：

[1] UNIV FERRARA,DIPARTIMENTO CHIM,I-44100 FERRARA,ITALY

[2] UNIV BOLOGNA,DIPARTIMENTO CHIM ORGAN A MANGINI,I-40136 BOLOGNA,ITALY

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 01期

关键词：

microbial reduction; methyl-substituted bicyclo[3.2.0]hept-3-en-6-ones; bicyclo[3.2.0]hept-2-en-6-one; bicyclo[3.30]oct-7-en-2-one;

D O I：

10.1016/0957-4166(95)00445-9

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Various yeast and mould strains were tested in the microbial reduction of methyl-substituted bicyclo[3.2.0]hept-3-en-6-ones 1a-c. The endo-alcohols 2a-c were obtained with good yields and enantiomeric excess, Lower yields are described for the eno-alcohols 3a-e which are normally enantiomerically pure. Comparisons with microbial reduction of bicyclo[3.2.0]hept-2-en-6-one 1d and bicyclo[3.3.0]oct-7-en-2-one 1e are also reported.

引用

页码：277 / 282

页数：6

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