Urinary glycosaminoglycan excretion in urolithiasis

被引：10

作者：

Akçay, T ^{[1
]}

Konukoglu, D ^{[1
]}

Dinçer, Y ^{[1
]}

机构：

[1] Istanbul Univ, Dept Biochem, Cerrahpasa Med Fac, Istanbul, Turkey

来源：

ARCHIVES OF DISEASE IN CHILDHOOD | 1999年 / 80卷 / 03期

关键词：

glycosaminoglycans; urolithiasis; renal stones;

D O I：

10.1136/adc.80.3.271

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Urinary glycosaminoglycan (GAG) excretion was measured in children with idiopathic urolithiasis (15 girls and 10 boys; mean (SD) age 6.2 (2.4) years) and in healthy controls (10 girls and 14 boys; mean (SD) age 6.8 (3.8) years). GAG excretion was expressed as a GAG/creatinine (mg/g) ratio and was evaluated using dimethylmethylene blue. In healthy control children, the mean (SD) GAG/creatinine ratio was 31.67 (12.76) and it was similar in girls and boys, The children with idiopathic urolithiasis had significantly lower mean (SD) GAG/creatinine ratios than controls (22.59 (7.35)). Therefore, urinary GAG excretion may be important in the disease process in children with urolithiasis, as it is in adults.

引用

页码：271 / 272

页数：2

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