Efficient synthesis of 3′-glycosylated LacNAc-based oligosaccharides

被引：17

作者：

Ding, YL ^{[1
]}

Fukuda, M ^{[1
]}

Hindsgaul, O ^{[1
]}

机构：

[1] Burnham Inst, La Jolla Canc Res Ctr, La Jolla, CA 92037 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1998年 / 8卷 / 14期

关键词：

D O I：

10.1016/S0960-894X(98)00332-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

LacNAc-based oligosaccharides, including sialyl-(2 --> 3)-LacNAc, dimeric sialyl-(2 --> 3) -LacNAc, trimeric sialyl-(2 --> 3)-LacNAc, beta-glucuronyl-(1 --> 3)-LacNAc, and 3-sulfo-beta-glucuronyl-(1 --> 3)-LacNAc, were synthesized efficiently from a single protected LacNAc derivative having both OH-3' and 4' unprotected. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1903 / 1908

页数：6

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