Micranoic acids A and B:: Two new octanortriterpenoids from Schisandra micrantha

被引：36

作者：

Li, RT ^{[1
]}

Han, QB ^{[1
]}

Zhao, AH ^{[1
]}

Sun, HD ^{[1
]}

机构：

[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 2003年 / 51卷 / 10期

关键词：

Schisandra micrantha; Schisandraceae; octanortriterpenoid; micranoic acid A; micranoic acid B;

D O I：

10.1248/cpb.51.1174

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two novel octanortriterpenoids, micranoic acids A (1) and B (2), along with three known compounds, kadsuric acid (3), 3beta-hydroxy-lanost-9(11),24(25)-dien-26-oic acid (4) and schizandronic acid (5), were isolated from the leaves and stems of Schisandra micrantha. The structures of 1 and 2 were determined by 1D and 2D NMR spectroscopic analysis. Micranoic acids A and B represent a new group of triterpenes in which the entire C-17 side chain has lost. This is the first report of octanortriterpenoids isolated from the family Schisandraceae.

引用

页码：1174 / 1176

页数：3

共 9 条

[1]

Dai P., 1990, CHEM RES CHINESE U, V11, P423

[2] Schisandra chinensis (Turcz.) Baill [J].

Hancke, JL ;

Burgos, RA ;

Ahumada, F .

FITOTERAPIA, 1999, 70 (05) :451-471

[3] Biologically active components from traditional Chinese medicines [J].

Li, LN .

PURE AND APPLIED CHEMISTRY, 1998, 70 (03) :547-554

[4] Micrandilactone A:: A novel triterpene from Schisandra micrantha [J].

Li, RT ;

Zhao, QS ;

Li, SH ;

Han, QB ;

Sun, HD ;

Lu, Y ;

Zhang, LL ;

Zheng, QT .

ORGANIC LETTERS, 2003, 5 (07) :1023-1026

[5]

LIU JS, 1980, ACTA CHIM SINICA, V38, P361

[6]

LONG KH, 1985, CHEM TERPENOIDS, P258

[7]

RAHMAN A, 1992, TETRAHEDRON, V48, P3577

[8] Nigranoic acid, a triterpenoid from Schisandra sphaerandra that inhibits HIV-1 reverse transcriptase [J].

Sun, HD ;

Qiu, SX ;

Lin, LZ ;

Wang, ZY ;

Lin, ZW ;

Pengsuparp, T ;

Pezzuto, JM ;

Fong, HHS ;

Cordell, GA ;

Farnsworth, NR .

JOURNAL OF NATURAL PRODUCTS, 1996, 59 (05) :525-527

[9]

TAKAHASHI K, 1975, CHEM PHARM BULL, V23, P538

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