Perisomatic inhibition

被引：518

作者：

Freund, Tamas F. ^{[1
]}

Katona, Istvan ^{[1
]}

机构：

[1] Hungarian Acad Sci, Inst Expt Med, H-1450 Budapest, Hungary

来源：

NEURON | 2007年 / 56卷 / 01期

基金：

匈牙利科学研究基金会;

关键词：

D O I：

10.1016/j.neuron.2007.09.012

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Recent evidence supports the hypothesis of a functional dichotomy of perisomatic inhibition in the cerebral cortex: the parvalbumin- and cholecystokinin-containing basket cells that are specialized to control rhythm (as a clockwork) and "mood" (as a fine-tuning device), respectively, of network oscillations. Pathology extends this conclusion further, as the former is implicated in epilepsy and the latter in anxiety. The well-balanced cooperation of the two inhibitory systems is required for the normal network operations underlying the cognitive functions of the cerebral cortex.

引用

页码：33 / 42

页数：10

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