Recent advances in polyaniline based biosensors

被引:427
作者
Dhand, Chetna [1 ,2 ]
Das, Maumita [1 ,2 ]
Datta, Monika [2 ]
Malhotra, B. D. [1 ]
机构
[1] CSIR, Natl Phys Lab, Biomed Instrumentat Sect, Mat Phys & Engn Div,Ctr Biomol Elect,Dept Sci & T, New Delhi 110012, India
[2] Univ Delhi, Dept Chem, New Delhi 110007, India
关键词
Biosensor; Polyaniline; Conducting polymers; Direct electron transfer; Nanostructure; Immunosensor; FREE ELECTROCHEMICAL DETECTION; LANGMUIR-BLODGETT-FILMS; NUCLEIC-ACID SENSOR; DNA HYBRIDIZATION; GLUCOSE-OXIDASE; BIOELECTROCHEMICAL CHARACTERISTICS; CONDUCTING POLYANILINE; ADENINE-DINUCLEOTIDE; CHOLESTEROL OXIDASE; IMMOBILIZATION;
D O I
10.1016/j.bios.2010.10.017
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
The present paper contains a detailed overview of recent advances relating to polyaniline (PANI) as a transducer material for biosensor applications. This conducting polymer provides enormous opportunities for binding biomolecules, tuning their bio-catalytic properties, rapid electron transfer and direct communication to produce a range of analytical signals and new analytical applications. Merging the specific nature of different biomolecules (enzymes, nucleic acids, antibodies, etc.) and the key properties of this modern conducting matrix, possible biosensor designs and their biosensing characteristics have been discussed. Efforts have been made to discuss and explore various characteristics of PANI responsible for direct electron transfer leading towards fabrication of mediator-less biosensors. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:2811 / 2821
页数:11
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