Analysis of macrolide antibiotics by liquid chromatography

被引：36

作者：

de la Huebra, MJG ^{[1
]}

Vincent, U ^{[1
]}

机构：

[1] Inst Reference Mat & Measurements, Directorate Gen Joint Res Ctr, European Commiss, B-2440 Geel, Belgium

来源：

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2005年 / 39卷 / 3-4期

关键词：

macrolide antibiotics; HPLC; biological samples; foodstuff;

D O I：

10.1016/j.jpba.2005.04.031

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A compilation of the most representative single and multianalyte HPLC methods for the analysis of macrolide antibiotics published during the last two decades is presented in this paper. Its scope is the coverage of two main areas which require the determination of macrolide antibiotics at a low concentration level, i.e. pharmacokinetic studies and residue analysis. Both of these areas involve the treatment of biological and foodstuff matrices, respectively. A detailed explanation of the different sample preparation procedures as well as the experimental conditions and the main analytical features are provided for each referred method in order to allow the reader to select the most suitable conditions for their particular purpose. (c) 2005 Elsevier B.V. All rights reserved.

引用

页码：376 / 398

页数：23

共 54 条

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