Proteinaceous inhibitors of endo-β-glucanases

被引:52
作者
York, WS
Qin, QA
Rose, JKC
机构
[1] Univ Georgia, Dept Biochem & Mol Biol, Complex Carbohydrate Res Ctr, Athens, GA 30602 USA
[2] Cornell Univ, Dept Plant Biol, Ithaca, NY 14853 USA
来源
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS | 2004年 / 1696卷 / 02期
基金
美国国家科学基金会;
关键词
plant; fungus; oomycete; pathogen; endoglucanase; cell wall;
D O I
10.1016/j.bbapap.2003.07.003
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Both plants and filamentous phytopathogens secrete proteins that inhibit endo-beta-glucanases. The first endo-beta-glucanase inhibitor proteins to be discovered are XEGIP, a tomato protein that inhibits fungal xyloglucan-specific endo-beta-1,4-glucanases, and GIP1, an oomycete protein that inhibits endo-beta-1,3-glucanases produced by the plant host. These inhibitor proteins act by forming high-affinity complexes with their endoglucanase ligands. A family of XEGIP-like proteins has been identified. At least one member of this family (extracellular dermal glycoprotein, EDGP) has been shown to have endoglucanase-inhibitor activity, while other members have sequence similarity to a xylanase inhibitor from wheat (TAXI-1). The oomycete inhibitor GIP1 is a catalytically inactive serine protease homolog (SPH) whose structure is unrelated to XEGIP. Both types of inhibitor proteins are likely to affect the interactions of plants with filamentous phytopathogens, and a basic model describing their roles in pathogenesis is proposed. (C) 2003 Elsevier B.V. All rights reserved.
引用
收藏
页码:223 / 233
页数:11
相关论文
共 81 条
  • [31] AMINO-ACID SEQUENCE OF BOVINE PROTEIN-Z - A VITAMIN-K-DEPENDENT SERINE PROTEASE HOMOLOG
    HOJRUP, P
    JENSEN, MS
    PETERSEN, TE
    [J]. FEBS LETTERS, 1985, 184 (02) : 333 - 338
  • [32] A cell adhesion protein from the crayfish Pacifastacus leniusculus, a serine proteinase homologue similar to Drosophila masquerade
    Huang, TS
    Wang, HY
    Lee, SY
    Johansson, MW
    Söderhäll, K
    Cerenius, L
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (14) : 9996 - 10001
  • [33] ISACKSON PJ, 1984, J BIOL CHEM, V259, P5380
  • [34] Jin W, 1999, GENETICS, V153, P445
  • [35] Resistance to oomycetes: a general role for the hypersensitive response?
    Kamoun, S
    Huitema, E
    Vleeshouwers, VGAA
    [J]. TRENDS IN PLANT SCIENCE, 1999, 4 (05) : 196 - 200
  • [36] Kawasaki KI, 1996, J JPN SOC FOOD SCI, V43, P146
  • [37] KEEN NY, 1983, PLANT PHYSIOL, V71, P446
  • [38] Enhanced genome annotation using structural profiles in the program 3D-PSSM
    Kelley, LA
    MacCallum, RM
    Sternberg, MJE
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2000, 299 (02) : 499 - 520
  • [39] KIM SH, 1995, J IMMUNOL, V154, P6073
  • [40] ACTION OF CELLULOLYTIC ENZYMES ON SUBSTITUTED CELLULOSES
    KLOP, W
    KOOIMAN, P
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1965, 99 (01) : 102 - &