New insights into the tumor suppression function of P27Kip1

[1] Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27(KIP1) [J]. MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (07) : 3850 - 3857

[2] Cyclin E and c-Myc promote cell proliferation in the presence of p16(INK4a) and of hypophosphorylated retinoblastoma family proteins [J]. EMBO JOURNAL, 1997, 16 (17) : 5322 - 5333

[3] A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27Kip1 [J]. EMBO JOURNAL, 1998, 17 (20) : 5987 - 5997

[4] The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase [J]. EMBO JOURNAL, 1996, 15 (19) : 5280 - 5289

[5] Decreased levels of the cell-cycle inhibitor p27(Kip1) protein: Prognostic implications in primary breast cancer [J]. NATURE MEDICINE, 1997, 3 (02) : 227 - 230

[6] CLURMAN BE, 1998, GENETIC BASIS HUMAN, P175

[7] Requirement of p27(Kip1) for restriction point control of the fibroblast cell cycle [J]. SCIENCE, 1996, 272 (5263) : 877 - 880

[8] Association of p27Kip1 levels with recurrence and survival in patients with stage C prostate carcinoma [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (12) : 916 - 920

[9] Esposito V, 1997, CANCER RES, V57, P3381

[10] A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice [J]. CELL, 1996, 85 (05) : 733 - 744

[1] Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27(KIP1) [J]. MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (07) : 3850 - 3857

[2] Cyclin E and c-Myc promote cell proliferation in the presence of p16(INK4a) and of hypophosphorylated retinoblastoma family proteins [J]. EMBO JOURNAL, 1997, 16 (17) : 5322 - 5333

[3] A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27Kip1 [J]. EMBO JOURNAL, 1998, 17 (20) : 5987 - 5997

[4] The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase [J]. EMBO JOURNAL, 1996, 15 (19) : 5280 - 5289

[5] Decreased levels of the cell-cycle inhibitor p27(Kip1) protein: Prognostic implications in primary breast cancer [J]. NATURE MEDICINE, 1997, 3 (02) : 227 - 230

[6] CLURMAN BE, 1998, GENETIC BASIS HUMAN, P175

[7] Requirement of p27(Kip1) for restriction point control of the fibroblast cell cycle [J]. SCIENCE, 1996, 272 (5263) : 877 - 880

[8] Association of p27Kip1 levels with recurrence and survival in patients with stage C prostate carcinoma [J]. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (12) : 916 - 920

[9] Esposito V, 1997, CANCER RES, V57, P3381

[10] A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice [J]. CELL, 1996, 85 (05) : 733 - 744